Better Care through Better Research

Since its inception in 1965, the Berman Center for Outcomes and Clinical Research has been a leader in cardiovascular research and a clinical site for over 100 trials in heart and kidney disease, diabetes, women’s health, cancer, and neurological disorders. For several of these trials, the Berman Center initiated the investigation, and was responsible for study design, implementation, and analysis. The Berman Center for Outcomes and Clinical Research is a division of Hennepin Healthcare Research Institute (HHRI), formerly known as Minneapolis Medical Research Foundation (MMRF), which is a subsidiary of Hennepin Healthcare System, Inc.

Hennepin Healthcare is an integrated system of care that includes HCMC, a nationally recognized Level 1 Adult Trauma Center and Level 1 Pediatric Trauma Center, medical research, and teaching hospital.

The Berman Center is compliant with Good Clinical Practice (GCP) and/or regulatory requirements consistent with “best practices” guidelines and focuses on outcomes to impact health policy and practice.

As was the intent of founder Dr. Reuben Berman, a pioneer in the field of cardiovascular clinical research, our primary mission is to empower the medical community to offer better patient care through better research.

Active Studies

  • ASPirin in Reducing Events in the Elderly (ASPREE)
    ASPREE is the largest international trial ever funded by the US National Institute on Aging (NIA), enrolling 19,000 participants age 65 or older in the US and Australia, randomizing them to either daily low dose aspirin or placebo.  This study will help answer questions as to whether or not daily aspirin use for…
  • Chronic Kidney Disease
    If you are interested or would like more information about BRINK, please call (612) 341-7904 or email The BRain In Kidney Disease Study (BRINK) The goal of this study is to learn how common memory problems are in patients with and without chronic kidney disease (CKD), and the possible causes of these…
  • Northstar: Addiction Medicine Clinical Research
    Substance Abuse Research The Northstar Node is member of the National Drug Abuse Treatment Clinical Trials Network (CTN), a means by which medical and specialty treatment providers, treatment researchers, participating patients, and the National Institute on Drug Abuse cooperatively develop, validate, refine, and deliver new treatment options to patients. This unique partnership enables…
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