SPS3, Secondary Prevention of Small Subcortical Strokes Trial

National Institute of Neurological Disorders and Stroke (NINDS), National Institutes of Health (NIH)

The goal of this study is to identify the optimal combinations of antiplatelet therapy (aspirin and clopidogrel vs. aspirin alone) and blood pressure control (intensive vs. less intensive control) for preventing recurrent strokes and cognitive decline in patients who have experienced a small sub-cortical stroke.